TYPES OF OVARIAN CANCER


EPITHELIAL -

  • Approximately 85%-90% of ovarian cancer cases; most common

  • Arise from the cells that cover the outer surface of the ovary

  • Tend to spread to the lining and organs of the abdomen and pelvis first, which can cause bloating due to ascites (fluid accumulation)

  • Risk factors:

  1. mENOPAUSE - MOST DEVELOP AFTER AGE 40

  2. NEVER HAVING A FULL-TERM PREGNANCY

  3. FIRST FULL-TERM PREGNANCY AFTER THE AGE OF 30

  4. MENSTRUATING BEFORE THE AGE OF 12

  5. USE OF FERTILITY DRUGS FOR LONGER THAN ONE YEAR

  6. A BODY MASS INDEX (BMI) OF AT LEAST 30

  7. NEVER HAVING USED ORAL CONTRACEPTIVES

  8. TAKING ANDROGENS (MALE HORMONES)

  9. ESTROGEN THERAPY AFTER MENOPAUSE

  10. FAMILY HISTORY OF OVARIAN, BREAST, OR COLORECTAL CANCER WITH BRCA1 AND BRCA2 GENETIC MUTATIONS

 

GERM CELL -

  • Approximately 5% of ovarian cancer cases

  • Arise from the cells that produce the eggs

  • Have a good prognosis with early detection and treatment, due to their slow growth rate

  • Tend to affect younger women

  • Risk factors:

  • more research is needed to better determine what these are - hence the need for organizations like ours to raise awareness and funds to support scientific studies.

 

STROMAL TUMOR -

  • Approximately 5% of ovarian cancer cases

  • Arise from the structural tissue cells of the ovary that also produce progesterone and estrogen, which are the female hormones

  • These tumors can produce androgens, or male hormones, like testosterone

  • Majority of cases affect women over 50, although younger women can have it

  • Have a good prognosis with early detection and treatment, due to their slow growth rate

  • Most common type is the granulosa cell tumor.  Other types are the Sertoli-Leydig cell tumor and granulosa-theca tumor

  • Risk factors:

  • MORE RESEARCH IS NEEDED TO BETTER DETERMINE WHAT THESE ARE - HENCE THE NEED FOR ORGANIZATIONS LIKE OURS TO RAISE AWARENESS AND FUNDS TO SUPPORT SCIENTIFIC STUDIES